This study was designed to research the clinical efficacy and tolerance of Diclofenac sodium, a potent inhibiter of prosta-glandin synthetase.
Total 53 cases of painful condition in orthopaedic field were treated with Diclofenac sodium, available for intramuscular injection, in department of orthopaedic surgery of Chungnam National University Hospital from Nov., 1986 to Jan., 1987. Among 53 cases of painful condition, The most common condition was rheumatoid arthritis and osteoarthritis (33cases; 60.3%), followed by sprain and strain(11cases; 20.8%), postoperative state(7cases ; 13.2%), ana others(3cases; 5.7%).
There was no predilection in age and sex distribution.
At thirty minutes after the injection 46/53patients treated with Diclofenac sodium had comp fete 31 (58.5%) or partial 15(28.3%) relief of pain.
Side effects were mild and transient.
It is concluded that intramuscular injection of Diclofenac sodium is effective in treatment of pain due to operative intervention & various disease in orthopaedic field.
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